温春霞

温春霞

邮箱：wenchunxia@lcu.edu.cn

教学科研简介

承担本科生病原微生物与医学免疫学相关课程讲授工作

主要从事病毒感染与天然免疫相关领域研究工作

讲授课程

• 本科生课程:医学微生物学、医学免疫学

• 研究生课程

主要研究方向

• 病毒与宿主互作

• 病毒致病机制研究

• 抗病毒疫苗研发

代表性科研项目

• 山东省青年科学基金，寨卡病毒感染星形胶质细胞致细胞程序性坏死分子机制的研究 2024.01-2026.12

• 校基金: 寨卡病毒感染引发ZBP1 激活中Z-NA的检测与来源

代表性论文

1. Wen C, Yu Y, Gao C, Qi X, Cardona CJ, Xing Z. 2022. Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus. PLoS One. 17(4):e0257408.

2. Yu Y, Gao C, Wen C, Zou P, Qi X, Cardona CJ, et al. 2022. Intrinsic features of zika virus non-structural proteins NS2A and NS4A in the regulation of viral replication. PLoS Neglect Tropical Diseases 16(5):e0010366.

3. Wen C, Yu Y, Gao C, Qi X, Cardona CJ, Xing Z. 2021. RIPK3-dependent necroptosis is induced and restricts viral replication in human astrocytes infected with zika virus. Frontiers in Cellular and Infection Microbiology 11:637710.

4. Gao C, Yu Y, Wen C, Li Z, Sun M, Gao S, et al. 2021. Peptides derived from viral glycoprotein Gc inhibit infection of severe fever with thrombocytopenia syndrome virus. Antiviral Research 194:105164.

5. Gao C, Wen C, Li Z, Lin S, Gao S, Ding H, et al. 2021. Fludarabine inhibits infection of zika virus, SFTS phlebovirus, and enterovirus A71. Viruses 13(5): 774

6. Wang L, Cao L, Wen C, Li J, Yu G, Liu C. 2020. LncRNA LINC00857 regulates lung adenocarcinoma progression, apoptosis and glycolysis by targeting miR-1179/SPAG5 axis. Hum Cell. 33(1):195-204.

7. Wang L, Jiang H, Shen SM, Wen CX, Xing Z, Shi Y. 2018. Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-kappaB signaling in human pulmonary endothelial cells infected with influenza A viruses. PLoS One 13(10):e0205344.

8. Wen C, Yuan Q, Liang H, Vriesekoop F. 2014. Preparation and stabilization of dlimonene pickering emulsions by cellulose nanocrystals. Carbohydrate Polymers

112:695-700.

9. Leveraging ZBP1 signalling for cancer immunology (Revision)