张琳

发布时间：2025-03-27

张琳

邮箱：zhanglin6425@163.com

张琳，理学博士、讲师。主要研究领域为环境内分泌干扰物暴露对配子发生和胚胎发育的影响机制及恢复研究。多项成果已在Journal of Hazardous Materials及Ecotoxicology and Environmental Safety等SCI期刊上发表。

孕期BaP暴露通过mTOR/HIF-1α信号通路导致F1雄鼠生精异常的机制及恢复机理研究，2025.01-2027.12，10万元，教育部辅助生殖重点实验室开放课题，在研，参与；
孕期苯并芘暴露通过PI3K/Akt/mTOR信号通路造成F1代雄鼠生殖损伤及淫羊藿苷的恢复机制研究，2025.01-2027.12，10万元，山东省自然科学基金面上项目，在研，参与。

Wang QY^#, Zhang L^#, Han XY, Wang DM, Ding ML, Cheng D, He QL^*, Liu SZ^*. 2,3',4,4',5-Pentachlorobiphenyl induces mitochondria-dependent apoptosis mediated by AhR/Cyp1a1 in mouse germ cells. Journal of Hazardous Materials, SCI一区，Top期刊，IF=14.224，共同一作
Zhang L^#, Chen WQ^#, Han XY, Wang HL, Gao PZ, Wang DM, Cao Z, Sun CH, Cheng D, Bai J^*, He QL^*, Liu SZ^*. Benzo(a)pyrene exposure during pregnancy leads to germ cell apoptosis in male mice offspring via affecting histone modifications and oxidative stress levels. Science of the Total Environment, SCI一区，Top期刊，IF=8.2，共同一作
He QL, Zhang L, Liu SZ^*. Effects of Polychlorinated Biphenyls on Animal Reproductive Systems and Epigenetic Modifications. Bulletin of Environmental Contamination and Toxicology, SCI四区，IF=2.7，二作
Tao YR^#, Zhang YT^#, Han XY, Zhang L, Jiang LG, Ma Y, Meng LJ, He QL^*, Liu SZ^*. Intrauterine exposure to 2,3',4,4',5-pentachlorobiphenyl alters spermatogenesis and testicular DNA methylation levels in F1 male mice. Ecotoxicology and Environmental Safety, SCI二区，Top期刊，IF=6.8，四作